Basic Information
VIS ID
TVIS44024588
Fusion event
HTLV-1-USP24 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p32.3
Reference genome
GRCh37/hg19
Start
55590140/55124467 (Hg38)
End
55590140/55124467 (Hg38)
Orient
+
Location type
splicing
Fragile sites / regions
FRA1B
Target gene
USP24
miRNAs that regulate target gene
hsa-mir-196a-5p ; hsa-let-7d-5p ; hsa-mir-1226-3p ; hsa-mir-935 ; hsa-mir-193b-3p ; hsa-mir-181b-5p
Nearest miRNA
hsa-mir-12136/Upstream/1070313; hsa-mir-101-1/Downstream/101174;
Nearest TSS
ENST00000473358/Upstream/29148; ENST00000451250/Downstream/29450;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/84125, chr1-CpG: 133/Downstream/90325
Upstream sequence
AGAGGGTCTCCCATTTTTGTGACTCTGGCAAACCTACACACAGAATTCTTATGGTTATTTCTTACCCAGTGTTCTCATTACTGTCTCTTTTTAATCAGTA
Downstream sequence
CCTGAACTGCTGAGTCTGTTTCGAATTCCAGCAGGACACAGGGAATTACTTTCTTTAATTGGCTGGCTACTCCCAACAAGATCAAGCCGTCCTGCAGCCG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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