Basic Information
VIS ID
TVIS44024614
Fusion event
HTLV-1-FPGT-TNNI3K integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh37/hg19
Start
74948529/74482845 (Hg38)
End
74948529/74482845 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
FPGT-TNNI3K
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-101-1/Upstream/3415129; hsa-mir-11399/Downstream/2577298;
Nearest TSS
ENST00000473358/Upstream/14332; ENST00000465473/Downstream/29769;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/284494, chr1-CpG: 40/Downstream/642287
Upstream sequence
TATGTAATGAATACAGGCAGTGTATCTTGTTAGCATTTCTACAGCTCATTTACCACCAATAAAAAAAGACCAGACTTTCAAAATGAGACGCACTTTGATA
Downstream sequence
ATAATCTGTTTCACTGGTACATCACTTAATCTTACTAATGCTGAACAATTGCAGTTCAGGTTTCTGATTCATTGATATTTCTTCCAGCTGGTGGTAGAGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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