Basic Information
VIS ID
TVIS44024618
Fusion event
HTLV-1-CAMTA1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.23
Reference genome
GRCh37/hg19
Start
7774791/7714731 (Hg38)
End
7774791/7714731 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
CAMTA1
miRNAs that regulate target gene
hsa-mir-129-5p ; hsa-mir-155-5p ; hsa-mir-218-5p ; hsa-mir-34a-5p ; hsa-mir-96-5p ; hsa-mir-124-3p ; hsa-mir-17-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p
Nearest miRNA
hsa-mir-12136/Upstream/1284835; hsa-mir-101-1/Downstream/1151771;
Nearest TSS
ENST00000473358/Upstream/13761; ENST00000476864/Downstream/21677;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/8935, chr1-CpG: 91/Downstream/56260
Nearest cancer related gene
CAMTA1(TSG, No orient, 0)
Upstream sequence
ttgcctcagcctcccgagtagctgggactccaggtgcgtgtcaccacacctggctaatttttgtatttttagcagagacggagtttcaccatgttggtca
Downstream sequence
ggctggtctcaaactcctgacctcaggtgatcttcccgcctcggcctcccaaaatgctgggattacaggtgtgagccaccacgtttggcccacagcatcc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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