Basic Information
VIS ID
TVIS44024640
Fusion event
HTLV-1-MRPS9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
105682762/105066304 (Hg38)
End
105682762/105066304 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
MRPS9
miRNAs that regulate target gene
hsa-mir-193b-3p
Nearest miRNA
hsa-mir-1285-2/Upstream/2633938; hsa-mir-10b/Downstream/4075186;
Nearest TSS
ENST00000437798/Upstream/27808; ENST00000413583/Downstream/22714;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/27991, chr2-CpG: 85/Downstream/77552
Upstream sequence
AGTGCTTTTTATCTGACATGGTATCTTTTGCTCTGTGGACCTTTTCCACAGTATTTGGTACAATACTTAGTATAGTGAGGGATTATAAATTAATAAGTGT
Downstream sequence
GTATTAATTTACTTTTAGCTGAGAAAAATTTTTAAAGGCAAAGACACATTTTCTGATACTTTCAGAAGACTTCTAGCGAATTCTTTGTTGGCTTGTTTTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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