Basic Information
VIS ID
TVIS44024644
Fusion event
HTLV-1-GCC2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
109083179/108466723 (Hg38)
End
109083179/108466723 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
GCC2
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-mir-193b-3p ; hsa-mir-5197-3p ; hsa-mir-9-3p ; hsa-mir-4422 ; hsa-mir-6835-3p ; hsa-mir-186-5p ; hsa-mir-3133
Nearest miRNA
hsa-mir-1285-2/Upstream/6034357; hsa-mir-10b/Downstream/674767;
Nearest TSS
ENST00000437798/Upstream/16839; ENST00000485546/Downstream/2577;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/17225, chr2-CpG: 90/Downstream/67151
Upstream sequence
caccacacctgactaattttttgtatttttagtagagatggggtttcactatgttagccaggatggtcccgatctcctgacctcatgatccacccacctc
Downstream sequence
aacctcccaaaatgctgggattacaggcatgagctacctgcacccggccAGcttatggtttcttgagtttaaagctgtgtttttgacatttaaatcttaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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