Basic Information
VIS ID
TVIS44024650
Fusion event
HTLV-1-NT5DC4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
113485558/112727981 (Hg38)
End
113485558/112727981 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2B
Target gene
NT5DC4
Nearest miRNA
hsa-mir-1285-2/Upstream/956847; hsa-mir-10b/Downstream/854978;
Nearest TSS
ENST00000437798/Upstream/1738; ENST00000491170/Downstream/1676;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/81479, chr2-CpG: 62/Downstream/36360
Nearby gene
CKAP2L(-8369) ;
Upstream sequence
CCAGCTGATGCGCTATGCCGACCTCTACACTGCCGCCTGCCTCGACCTCCTGTACTTCCGAGTGAGCTCAGCTCTCTCGGGCGGCCCCGGAGTTGGTGGG
Downstream sequence
TCCCTGCGGAATCTCCACGGCTGTTTGTGAACATTTATCCTAGAAGGACCCACTGGTCCCCAGCCTTGCTAGGAGCTTGCAAGGTCACCAGCCCTAATCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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