Basic Information
VIS ID
TVIS44024653
Fusion event
HTLV-1-ACTR3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
114649875/113892298 (Hg38)
End
114649875/113892298 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2B
Target gene
ACTR3
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-mir-1285-2/Upstream/170930; hsa-mir-10b/Downstream/13531239;
Nearest TSS
ENST00000437798/Upstream/1700; ENST00000489779/Downstream/35071;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1563, chr2-CpG: 92/Downstream/86978
Upstream sequence
CTTAAGTGACCTCCTTTCCTAAAGGGCAACCTTGAATTTAAAACATGCTGAATGACCAGTAGGATCGGGAAGAGGGGTTCAATTTAACCTAGGCTATTTC
Downstream sequence
TGTTTTAAAATTACGATTATCACAATAGTGTATTTTTAAGTTATTACATTGGTTTCTCCAATAAGGAGAGGTTATTAACTGCACATTGATGATTTGAATG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate