Basic Information
VIS ID
TVIS44024665
Fusion event
HTLV-1-EPB41L5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
120866101/120108525 (Hg38)
End
120866101/120108525 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
EPB41L5
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-1285-2/Upstream/6387157; hsa-mir-10b/Downstream/7315012;
Nearest TSS
ENST00000437798/Upstream/7815; ENST00000488691/Downstream/52042;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/94950, chr2-CpG: 134/Downstream/114231
Upstream sequence
TTAAGATTTGTAAGAAATTGCAGATTCCTTAATAAAGCTCGCATCTACAGACATGACTAATCATTGATAATAATAAATGCAAAATATTTTAAATTATTAG
Downstream sequence
GGGTAGAGTTAAAAAATGAAAAATAAAAGGTTATGATAATAGGAAGATGATTGCTGGCTTGATTTACCTTGTGGAACTAGTTAGAGGAGTATTCAGATAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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