Basic Information
VIS ID
TVIS44024672
Fusion event
HTLV-1-WDR33 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
128536166/127778592 (Hg38)
End
128536166/127778592 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
WDR33
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-186-5p ; hsa-mir-1-3p ; hsa-mir-98-5p ; hsa-mir-93-5p ; hsa-mir-19b-3p ; hsa-let-7b-5p ; hsa-mir-1914-3p ; hsa-mir-877-3p ; hsa-mir-615-3p ; hsa-mir-106b-5p ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-3189-5p ; hsa-mir-4758-3p ; hsa-mir-5699-5p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-4431 ; hsa-mir-96-5p ; hsa-mir-1271-5p ; hsa-mir-183-5p ; hsa-mir-8058 ; hsa-mir-5009-5p ; hsa-mir-422a ; hsa-mir-570-3p ; hsa-mir-378i ; hsa-mir-378h ; hsa-mir-378f ; hsa-mir-378e ; hsa-mir-378d ; hsa-mir-378c ; hsa-mir-378b ; hsa-mir-378a-3p ; hsa-mir-4766-5p ; hsa-mir-146a-3p
Nearest miRNA
hsa-mir-1285-2/Upstream/354974; hsa-mir-10b/Downstream/3712568;
Nearest TSS
ENST00000437798/Upstream/77084; ENST00000609350/Downstream/32361;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/64771, chr2-CpG: 65/Downstream/32155
Upstream sequence
CTGACTACCTGCCAGACAATGAACACACACACACACACACATTCTGTTCTCAAGAGTCTGACCGTTTCTCAGTACAGAAGAGCTCAAAAGAACAATGTGA
Downstream sequence
GAAGTTACTACTACACTGAGACACTACTACGCTGTGTGAGAGGCACTATTACAAGGGATATAGCACAGGAAACTTACAGCACCAATCAGCCTTAAGAAGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate