Basic Information
VIS ID
TVIS44024685
Fusion event
HTLV-1-KIF5C integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
149666599/148909030 (Hg38)
End
149666599/148909030 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
KIF5C
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-106b-5p ; hsa-mir-222-3p ; hsa-mir-183-5p ; hsa-mir-17-5p ; hsa-mir-376a-3p ; hsa-mir-382-5p ; hsa-mir-485-5p ; hsa-mir-466 ; hsa-mir-4672 ; hsa-mir-3941 ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-610 ; hsa-mir-216b-3p ; hsa-mir-4724-3p
Nearest miRNA
hsa-mir-128-1/Upstream/8322345; hsa-mir-10b/Downstream/421248;
Nearest TSS
ENST00000437798/Upstream/20207; ENST00000450621/Downstream/38267;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/20765, chr2-CpG: 23/Downstream/101110
Upstream sequence
TGGCACAAAAGCAGTGAAGTCCCTGAAAATACCAGCCAAATTTCACCTGAGCATATATTATAGAGCTTTAAAGTACCTAGAAGAGAAAAACCGCTTCTTT
Downstream sequence
CCCAGCTTCTTTGCCTCCCAGGCACCACATCACCACAGAGCAGCCAAAACAGAAACCAGATCAGGCCATTCATTTGCTTCAAGGTACGTTACACATGTAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate