Basic Information
VIS ID
TVIS44024697
Fusion event
HTLV-1-PKP4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
159506482/158649970 (Hg38)
End
159506482/158649970 (Hg38)
Orient
-
Location type
Intronic
Target gene
PKP4
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-218-5p ; hsa-mir-449a
Nearest miRNA
hsa-mir-128-1/Upstream/7281559; hsa-mir-10b/Downstream/536865;
Nearest TSS
ENST00000437798/Upstream/7450; ENST00000483881/Downstream/12272;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/191669, chr2-CpG: 146/Downstream/318372
Upstream sequence
ATGATGCTCTATAGCTTGCAGCTGGAGGCACCTTTGTCTCTAAGCTTCTGCCAGCACCAGACAACTGGGTTGAAGATCTAGTGCAGTTACAGATGAGCAA
Downstream sequence
GTGTGTTCCTGGAACATGTAGGTCAGCTGTGGAGTATATGACTTCAGTGACAGTTTCTTGGGCAAATCTCTATGATAGTGTAACTGTGACAGTATAAATG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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