Basic Information
VIS ID
TVIS44024703
Fusion event
HTLV-1-SCN2A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
166081364/165224854 (Hg38)
End
166081364/165224854 (Hg38)
Orient
-
Location type
Intronic
Target gene
SCN2A
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-128-1/Upstream/4816972; hsa-mir-10b/Downstream/3358089;
Nearest TSS
ENST00000437798/Upstream/20787; ENST00000486878/Downstream/14518;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/382471, chr2-CpG: 94/Downstream/568545
Nearby gene
SCN2A(+14548) ;
Upstream sequence
agtatatatgtatgtaagtgtatgtgggtgtttgtgtgtAGTCTCTTCTGTATATACCCATATATATATTGCTGTTTGTGTGGTGGTAAACTTCCCTTTT
Downstream sequence
CAAGGAAGGGATTACTTTATAAAGAGTCAAAAGTTTAAAATGAAAATAATCTGAAAAGCAATTCCTCACTTTCTCACAAACTCTGAGACTGAGTCCTTAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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