Basic Information
VIS ID
TVIS44024715
Fusion event
HTLV-1-METTL5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
170676865/169820355 (Hg38)
End
170676865/169820355 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2G
Target gene
METTL5
Nearest miRNA
hsa-mir-128-1/Upstream/1237337; hsa-mir-10b/Downstream/5347278;
Nearest TSS
ENST00000437798/Upstream/7180; ENST00000477461/Downstream/874;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/21108, chr2-CpG: 75/Downstream/6995
Upstream sequence
AAACTATGCATGTCTTTTCCTACCCTCACTGACTTCCTAACCTCCTTGCCCACAGTACACACAAAATTAACAGCCACGGTGAGTCACTGTTACTGATGGG
Downstream sequence
CACATGTAGAAACCCTTGGGTCTGTTAAGACATTAAAAAACAGATTCTGAAAGTATAAAATTCTTTCTATGTTTCGTATTCATTCATAAGGGTTAGGCAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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