Basic Information
VIS ID
TVIS44024718
Fusion event
HTLV-1-MAP3K20 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
174027284/173162556 (Hg38)
End
174027284/173162556 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2G
Target gene
MAP3K20
miRNAs that regulate target gene
hsa-mir-874-3p ; hsa-mir-6807-5p ; hsa-mir-146b-3p ; hsa-mir-6799-3p ; hsa-mir-3173-5p ; hsa-mir-7976 ; hsa-mir-4749-3p ; hsa-mir-210-5p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-6752-3p
Nearest miRNA
hsa-mir-128-1/Upstream/4579538; hsa-mir-10b/Downstream/2005077;
Nearest TSS
ENST00000437798/Upstream/2546; ENST00000435616/Downstream/45056;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/86013, chr2-CpG: 86/Downstream/192249
Upstream sequence
gggcggctcacctgaggtcaggagtttgagaccagcctggccagcatggtgaaacctcatctgtactaaaaatacaaaaattagccaggtgtggtggtag
Downstream sequence
gcgcctgtaatcccagctactcaggaggctgaggcaggagaatcgcttgaacccaggaggcggaggttgcagtgagtcaagattgcgccattgcactcca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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