Basic Information
VIS ID
TVIS44024719
Fusion event
HTLV-1-SP3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
174784254/173919526 (Hg38)
End
174784254/173919526 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2G
Target gene
SP3
miRNAs that regulate target gene
hsa-mir-27a-3p ; hsa-mir-223-3p ; hsa-mir-124-3p ; hsa-mir-484 ; hsa-mir-1260b ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-128-1/Upstream/5336508; hsa-mir-10b/Downstream/1248107;
Nearest TSS
ENST00000437798/Upstream/2694; ENST00000605739/Downstream/43853;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/563886, chr2-CpG: 54/Downstream/44076
Upstream sequence
GCACTTAAGTTTACATCTTCCTTGGTATCTCAGTATAGATGACAGGAAAACACTTTTTTTTACTGTGCTGTATTAGTGTCCTACATGGTGGCTAGTTATT
Downstream sequence
CTTAGAAATCCACTATTTATAAGGCTCAGGAGAAACAAAAGTAATAATCCatcaaaatgacccataaaagtaagaaaaggtattcaacattgttaaatat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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