Basic Information
VIS ID
TVIS44024721
Fusion event
HTLV-1-PDE11A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
178820026/177955299 (Hg38)
End
178820026/177955299 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2G
Target gene
PDE11A
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-1273e ; hsa-mir-6807-5p ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-4786-5p ; hsa-mir-6840-3p ; hsa-mir-199b-5p ; hsa-mir-199a-5p ; hsa-mir-665 ; hsa-mir-4302 ; hsa-mir-4433a-3p ; hsa-mir-335-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-3157-5p ; hsa-mir-30a-3p ; hsa-mir-876-3p ; hsa-mir-323a-5p ; hsa-mir-4691-3p ; hsa-mir-3910 ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-383-3p ; hsa-mir-433-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-1827 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p
Nearest miRNA
hsa-mir-10b/Upstream/641417; hsa-mir-1244-1/Downstream/1905537;
Nearest TSS
ENST00000437798/Upstream/28290; ENST00000493048/Downstream/117456;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/336244, chr2-CpG: 23/Downstream/117569
Upstream sequence
TTTAATGAGAAGCATGGTGGTATTTATGGTTTTATAGCCTGGAATGGCTAACTTGTTTGTTTGTTTCCtgagaatttaatgaaagctgagtatgtgtata
Downstream sequence
catatataattttatgtagaatttcagtgggttcacaaatcacccacaattccctgagagttcacagatcccaggttaagaagtcctgCTTTGCAGACTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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