Basic Information
VIS ID
TVIS44024732
Fusion event
HTLV-1-MYO1B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
192163188/191298462 (Hg38)
End
192163188/191298462 (Hg38)
Orient
+
Location type
Intronic
Target gene
MYO1B
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-378a-5p ; hsa-mir-363-3p ; hsa-mir-4703-3p ; hsa-mir-145-3p ; hsa-mir-6780b-3p ; hsa-mir-4698 ; hsa-mir-7852-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-3646 ; hsa-mir-561-3p ; hsa-mir-3662
Nearest miRNA
hsa-mir-10b/Upstream/2165351; hsa-mir-1244-1/Downstream/15484772;
Nearest TSS
ENST00000437798/Upstream/21577; ENST00000496992/Downstream/71102;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/52248, chr2-CpG: 88/Downstream/379385
Upstream sequence
AGCCCCTGTGATGAAATACTTTATTTGATACCTGAATATTTTAAATTCTAGTCCTCAAAGCCCCActtctcaaagtatggtgcttggaccaattgtatca
Downstream sequence
gaattcccccaggggcttatgaaaaaatctggattcctaggtcttacttctcataagccaggaatctacatttttcacaagctttctgggtgattcttag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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