Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene200624368200510008200583782200488952200519784200508729200511003200525401200527374200546499200546735200532278200532356200556660
Basic Information
VIS ID
TVIS44024736
Fusion event
HTLV-1-SGO2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
201421383/200556660 (Hg38)
End
201421383/200556660 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2I
Target gene
SGO2
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-335-3p ; hsa-mir-3613-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac
Nearest miRNA
hsa-mir-10b/Upstream/11423549; hsa-mir-1244-1/Downstream/6226574;
Nearest TSS
ENST00000437798/Upstream/21519; ENST00000454629/Downstream/29208;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/30166, chr2-CpG: 47/Downstream/29143
Upstream sequence
catggaggggaagagaatcaacaaatgataaagatcacacagatatcaaccagaaagtactcattccctaagctgggtattgaacccaagctgccatagt
Downstream sequence
gaaaagacaaagccttcgccagtaagctacagcattgggcagtttccattacccttcccagaaggaccttacagcagccaattttgagcttgcaaaggct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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