Basic Information
VIS ID
TVIS44024748
Fusion event
HTLV-1-BARD1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
GRCh37/hg19
Start
215619745/214755021 (Hg38)
End
215619745/214755021 (Hg38)
Orient
+
Location type
Intronic
Target gene
BARD1
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-193b-3p ; hsa-mir-215-5p ; hsa-mir-182-5p ; hsa-mir-3942-3p ; hsa-mir-6802-3p ; hsa-mir-610 ; hsa-mir-6501-3p ; hsa-mir-500b-3p ; hsa-mir-4760-3p
Nearest miRNA
hsa-mir-10b/Upstream/996862; hsa-mir-1244-1/Downstream/3145492;
Nearest TSS
ENST00000437798/Upstream/2543; ENST00000420134/Downstream/54621;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1470319, chr2-CpG: 110/Downstream/54250
Nearest cancer related gene
BARD1(OG, No orient, 0)
Upstream sequence
TTTGGAAGTAGATGTAAGTTTACATGTGGGACGTTCAAAGACCATAGCAAGAGAAGATGGGGCATGTGTAAGATTTCTTATTATTTGGGCACAATAATGT
Downstream sequence
GTGCTTTCTTCCCACTGATGTATTTTAACAGACTAACACTTTAGTTAGAGAATTAGTGTGAAAAATCAATTTAAAATACACAGAGGTGGATTTTATTCCC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate