Basic Information
VIS ID
TVIS44024749
Fusion event
HTLV-1-MREG integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
GRCh37/hg19
Start
216813842/215949119 (Hg38)
End
216813842/215949119 (Hg38)
Orient
+
Location type
Intronic
Target gene
MREG
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-130b-3p ; hsa-mir-26b-5p ; hsa-mir-19b-3p ; hsa-mir-106a-3p ; hsa-mir-122-5p ; hsa-mir-1307-3p ; hsa-mir-130a-3p ; hsa-mir-144-5p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3135b ; hsa-mir-3652 ; hsa-mir-3666 ; hsa-mir-3925-5p ; hsa-mir-4295 ; hsa-mir-4430 ; hsa-mir-454-3p ; hsa-mir-4638-5p ; hsa-mir-4712-3p ; hsa-mir-488-5p ; hsa-mir-504-3p ; hsa-mir-589-5p ; hsa-mir-6812-3p ; hsa-mir-95-5p
Nearest miRNA
hsa-mir-10b/Upstream/2190960; hsa-mir-1244-1/Downstream/1951394;
Nearest TSS
ENST00000437798/Upstream/7400; ENST00000455479/Downstream/64494;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/512982, chr2-CpG: 51/Downstream/64057
Upstream sequence
tggcaaaaccctgtctctactactactactactactactactactactactactactactactactactaataataataataataatacaaaaattagct
Downstream sequence
ggaggtggtggcacacacctgtaatcccagctactcaggaggctgaggcaggagaatcacttcaactcaggaggcagaggttgcagtgcgcagagatcgc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate