Basic Information
VIS ID
TVIS44024753
Fusion event
HTLV-1-WNT10A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
GRCh37/hg19
Start
219746957/218882235 (Hg38)
End
219746957/218882235 (Hg38)
Orient
-
Location type
Exonic
Target gene
WNT10A
miRNAs that regulate target gene
hsa-mir-130a-3p ; hsa-mir-1231 ; hsa-mir-203b-3p ; hsa-mir-27a-5p ; hsa-mir-3120-5p ; hsa-mir-378g ; hsa-mir-4486 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-4539 ; hsa-mir-361-3p ; hsa-mir-5685 ; hsa-mir-4690-3p ; hsa-mir-4724-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-378a-3p ; hsa-mir-2909 ; hsa-mir-3911 ; hsa-mir-4455 ; hsa-mir-6081 ; hsa-mir-6752-5p ; hsa-mir-7847-3p
Nearest miRNA
hsa-mir-10b/Upstream/59081; hsa-mir-1244-1/Downstream/119410;
Nearest TSS
ENST00000437798/Upstream/74; ENST00000483911/Downstream/1615;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1306, chr2-CpG: 63/Downstream/1355
Nearest cancer related gene
WNT10A(OG, No orient, 0)
Upstream sequence
CCCACTCCACCCCATATGTCTGCAGGTCAGCACCCAATGACATTCTGGACCTCCGCCTCCCCCCGGAGCCCGTGCTCAATGCCAACACAGTGTGCCTAAC
Downstream sequence
ATTGCCAGGCCTGAGCCGGCGGCAGATGGAGGTGTGTGTGCGTCACCCTGATGTGGCTGCCTCAGCCATACAGGGCATCCAGATCGCCATCCACGAATGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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