Basic Information
VIS ID
TVIS44024757
Fusion event
HTLV-1-FAM124B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q36.2
Reference genome
GRCh37/hg19
Start
225264369/224399652 (Hg38)
End
225264369/224399652 (Hg38)
Orient
+
Location type
Intronic
Target gene
FAM124B
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10b/Upstream/4493087; hsa-mir-1244-1/Downstream/610809;
Nearest TSS
ENST00000437798/Upstream/360333; ENST00000620050/Downstream/2342;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/359634, chr2-CpG: 65/Downstream/42531
Upstream sequence
ACAGGATATTTTGCTGTGAACATGACATTCATCCCCCTGCTTGCACATTTACACACATACACTGGACTGCAGCGGCTGACCACATGAACTTTGAGGGTAG
Downstream sequence
ATAGATACTTCCTatcttgggcaaataactgaccccctggaaagctcagttttcttatctccaaaatgggaaaaatagtaacttcataggttgttataag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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