Basic Information
VIS ID
TVIS44024761
Fusion event
HTLV-1-INPP5D integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q37.1
Reference genome
GRCh37/hg19
Start
234097626/233188980 (Hg38)
End
234097626/233188980 (Hg38)
Orient
-
Location type
Intronic
Target gene
INPP5D
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-26b-5p ; hsa-mir-93-3p
Nearest miRNA
hsa-mir-10b/Upstream/638407; hsa-mir-149/Downstream/4321951;
Nearest TSS
ENST00000437798/Upstream/18606; ENST00000491070/Downstream/6457;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/128372, chr2-CpG: 41/Downstream/15297
Upstream sequence
GATATAGTGAGTCTGCCCTGTTGGCCAACATGGTGCCCAGAGCCCTGTACCAGGAGCCTTTTGGTGTCTGGAAAGGAAGGGAGGGAATCGCCTAGAACAA
Downstream sequence
AGTATCACCTTTTTATTTGGCCCTTCTGTATGGGAGTCATCGTGAGAAACAGCCCCACATCTGAAAAAGTCATAACTCGTGGCAGACGAGGAGCTAGTGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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