Basic Information
VIS ID
TVIS44024764
Fusion event
HTLV-1-KLHL29 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p24.1
Reference genome
GRCh37/hg19
Start
23814204/23591334 (Hg38)
End
23814204/23591334 (Hg38)
Orient
+
Location type
Intronic
Target gene
KLHL29
miRNAs that regulate target gene
hsa-mir-127-5p
Nearest miRNA
hsa-mir-3125/Upstream/4242829; hsa-mir-10b/Downstream/1737306;
Nearest TSS
ENST00000437798/Upstream/58749; ENST00000288548/Downstream/51058;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/28865, chr2-CpG: 22/Downstream/37636
Upstream sequence
aagaggccggtgcccttggggcAATTTAGCTGTATCTCTCCGGCTGCCCTGCAGACTAAACAGGACAAGGAAAGAGCCAGGACACAGTCCGCAGGCTCCT
Downstream sequence
GTGTCCTGTCCCGTCCCAGGCCAGCCCTCTCTGTGCTCCTGAGCCACATGACAGCTGCTTCCTGGGCAGAGCCTTGGGCGTCCACAGCACTTCAGACTCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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