Basic Information
VIS ID
TVIS44024775
Fusion event
HTLV-1-FKBP1B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p23.3
Reference genome
GRCh37/hg19
Start
24274956/24052086 (Hg38)
End
24274956/24052086 (Hg38)
Orient
-
Location type
Intronic
Target gene
FKBP1B
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-26b-5p ; hsa-mir-24-3p ; hsa-mir-34a-5p
Nearest miRNA
hsa-mir-3125/Upstream/4703581; hsa-mir-10b/Downstream/1276554;
Nearest TSS
ENST00000437798/Upstream/2315; ENST00000421839/Downstream/1825;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1643, chr2-CpG: 99/Downstream/24013
Upstream sequence
tcccgtcttccctatctcaggaaatagttgcactattcatccagttgcccaaacagaaaacccaagcatcgttcttgttgtctcctttgtcctcatcctg
Downstream sequence
gaccccatttccagtctgattgcatgacctgtcagctccgcttcgaaaatatgtctccaatctttcactctcttctctgctgccaccaccttaaatcaag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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