Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene240687220240586716240617705240605431240631259240565804240581372240620385240627600240583495240587955240582700240586699240578152240581287240603804240606866240611634240613321240596901240598427240595724240595873240618984240619043240626512
Basic Information
VIS ID
TVIS44024777
Fusion event
HTLV-1-GPR35 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q37.3
Reference genome
GRCh37/hg19
Start
241565929/240626512 (Hg38)
End
241565929/240626512 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2J
Target gene
GPR35
miRNAs that regulate target gene
hsa-mir-4480 ; hsa-mir-3185 ; hsa-mir-451b ; hsa-mir-6864-5p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-298 ; hsa-mir-6828-5p ; hsa-mir-3179 ; hsa-mir-7515 ; hsa-mir-6783-5p
Nearest miRNA
hsa-mir-10b/Upstream/170423; hsa-mir-3133/Downstream/851393;
Nearest TSS
ENST00000437798/Upstream/1267; ENST00000438013/Downstream/921;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/3019, chr2-CpG: 35/Downstream/3762
Upstream sequence
atggggtctcagagtggggtgaggctgtgatggggAGTCTCAGTGAGGTGAGGCTGTGTTGGGGTCTCAGGTGGGCTGAGGCTGTTGGGGTCTCAGGGGT
Downstream sequence
GGCTGAGGCTGATGAAGACTTGGAGCCTGTGTCTGGGTAGCAGCTTGTTGGAGTGTGGGATGTGACATTTAAAAACAAGAATGAAGAATACCCCGTGCTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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