Basic Information
VIS ID
TVIS44024778
Fusion event
HTLV-1-SNED1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q37.3
Reference genome
GRCh37/hg19
Start
242021315/241081900 (Hg38)
End
242021315/241081900 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2J
Target gene
SNED1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-4666b ; hsa-mir-5011-3p ; hsa-mir-4775 ; hsa-mir-506-3p ; hsa-mir-124-3p ; hsa-mir-6815-3p ; hsa-mir-103a-2-5p ; hsa-mir-135b-5p ; hsa-mir-135a-5p ; hsa-mir-590-3p ; hsa-mir-4753-5p
Nearest miRNA
hsa-mir-10b/Upstream/625811; hsa-mir-3133/Downstream/396005;
Nearest TSS
ENST00000437798/Upstream/10494; ENST00000498170/Downstream/12476;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/16214, chr2-CpG: 59/Downstream/20228
Upstream sequence
GGGGCTTGGCCTCAGGGCGCCCCTTCCAACACAGCCTGTGCCTCAGCCTAGGACTGCTGGGCCACAGCTGGGTTTGCCACGGGAGCCTCCAAACGATGAG
Downstream sequence
GTGCCAGACAGGGAGTCTGGTGCACGGGGCTGACCCCTGAGCCCCCAGGGGCTGCGCTGCTGCCCCAAGCACCAGGATGAGAGGTGCTGCCCATCACGGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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