Basic Information
VIS ID
TVIS44024780
Fusion event
HTLV-1-ADCY3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p23.3
Reference genome
GRCh37/hg19
Start
25095537/24872668 (Hg38)
End
25095537/24872668 (Hg38)
Orient
-
Location type
Exonic
Target gene
ADCY3
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-1301-3p ; hsa-mir-1296-5p ; hsa-mir-877-5p
Nearest miRNA
hsa-mir-3125/Upstream/5524163; hsa-mir-10b/Downstream/455972;
Nearest TSS
ENST00000437798/Upstream/30076; ENST00000421904/Downstream/24;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/78910, chr2-CpG: 129/Downstream/46935
Upstream sequence
CCTGCTGCTGGCTCTGCTCTTCCAGGTTCATCTTCACCTCCAGCGACTGGCGGGCCTCCAGGAAGGCCTTGCGGTGCTTGCGGTCAGCCATGTAGTAGGA
Downstream sequence
CATGATGCCCACAGCGATGGCGCACAGGTAGAGGAAGACGTTGGCCAGGATCTGCACCCCAAGGAAGAAGAGAGAAAAGGCCAGGGGTGAAGGCACGTCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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