Basic Information
VIS ID
TVIS44024782
Fusion event
HTLV-1-GAREM2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p23.3
Reference genome
GRCh37/hg19
Start
26403596/26180727 (Hg38)
End
26403596/26180727 (Hg38)
Orient
+
Location type
UTR5
Target gene
GAREM2
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-421 ; hsa-mir-193b-3p ; hsa-mir-29a-3p
Nearest miRNA
hsa-mir-1301/Upstream/852006; hsa-mir-10b/Downstream/1815640;
Nearest TSS
ENST00000437798/Upstream/11; ENST00000496070/Downstream/4505;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1577, chr2-CpG: 115/Downstream/3826
Upstream sequence
cttttttgagacagagtctcgctctgttgcccaggctggagagcagtggtgtgatctcagctcactgcaacctctgccttccaggttcaagcgattcccc
Downstream sequence
tgcctcagcctcccaagtagctgggactacaggtgtgtgccaccacacccagagagttttttgtatttttagtagagatggggtttcaccatgttggcca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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