Basic Information
VIS ID
TVIS44024785
Fusion event
HTLV-1-SNX17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p23.3
Reference genome
GRCh37/hg19
Start
27596728/27373861 (Hg38)
End
27596728/27373861 (Hg38)
Orient
+
Location type
Exonic
Target gene
SNX17
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-18a-3p ; hsa-mir-6806-5p ; hsa-mir-4257 ; hsa-mir-6822-5p ; hsa-mir-6750-5p ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-6873-5p ; hsa-let-7i-5p ; hsa-mir-4458 ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-mir-98-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-4500 ; hsa-mir-19b-3p ; hsa-mir-19a-3p
Nearest miRNA
hsa-mir-1301/Upstream/2045140; hsa-mir-10b/Downstream/622506;
Nearest TSS
ENST00000437798/Upstream/3196; ENST00000493711/Downstream/547;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/2629, chr2-CpG: 24/Downstream/4613
Upstream sequence
TGAGAATAAAGACACACAAGGGACCTAGAAATAGAGTTGGGCATAGGTCAAGGCAAGGGACAAGGCAGTGCTTCCCATCCCCATGTGTGCTCACAACAGG
Downstream sequence
AGACACAGCAGGTCCCCACAGAGGAAGTGTCCTTGGAAGTGCTGCTCAGCAACGGGCAGAAAGTTCTGGTCAACGTGCTAACTTCAGATCAGACTGAGGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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