Basic Information
VIS ID
TVIS44024788
Fusion event
HTLV-1-ALK integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p23.1
Reference genome
GRCh37/hg19
Start
30022867/29800001 (Hg38)
End
30022867/29800001 (Hg38)
Orient
-
Location type
Intronic
Target gene
ALK
miRNAs that regulate target gene
hsa-mir-132-3p ; hsa-mir-96-5p
Nearest miRNA
hsa-mir-1301/Upstream/1803552; hsa-mir-10b/Downstream/2732152;
Nearest TSS
ENST00000437798/Upstream/82301; ENST00000421411/Downstream/90370;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/683958, chr2-CpG: 147/Downstream/119964
Nearest cancer related gene
ALK(OG, No orient, 0)
Upstream sequence
CCAGCATCCTTGCATTCatctattcattcagcacacctgtgttcagaactttctctgtacctggcactgtgccgcattagggtgcagaataggacaaagc
Downstream sequence
tccggactccaagtaggggaggtgaacatgcaaagtaacaaccataattcagtgtggTGCGTGCCGTGCTCTAAGAATGATGACAGTCCGGAATGAGGAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate