Basic Information
VIS ID
TVIS44024794
Fusion event
HTLV-1-MEMO1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
32175649/31950580 (Hg38)
End
32175649/31950580 (Hg38)
Orient
+
Location type
Intronic
Target gene
MEMO1
miRNAs that regulate target gene
hsa-mir-4642 ; hsa-mir-580-3p ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-3649 ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-657 ; hsa-mir-3665 ; hsa-mir-645 ; hsa-mir-4442 ; hsa-mir-3687 ; hsa-mir-4712-3p ; hsa-mir-6865-5p ; hsa-mir-6815-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-4797-5p ; hsa-mir-3929 ; hsa-mir-324-5p ; hsa-mir-129-5p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-4477a ; hsa-mir-2115-5p
Nearest miRNA
hsa-mir-1301/Upstream/3954131; hsa-mir-10b/Downstream/581573;
Nearest TSS
ENST00000437798/Upstream/7197; ENST00000605811/Downstream/12718;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/368867, chr2-CpG: 174/Downstream/59004
Upstream sequence
tgcccaggcaagcagatcacttgaggtcaggaatttgagaccagcctggccaacatggtgaaaccccatctctactaaaaacacaagaaaaaactagcca
Downstream sequence
ggcatggtggcgcacacctgtaatcccagatttgggaggctgaggcacgagaatcgcttgaacctgggaagcggaggttgcagtgagctgagataacgac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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