Basic Information
VIS ID
TVIS44024795
Fusion event
HTLV-1-NLRC4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
32479956/32254887 (Hg38)
End
32479956/32254887 (Hg38)
Orient
+
Location type
Intronic
Target gene
NLRC4
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1301/Upstream/4258438; hsa-mir-10b/Downstream/277266;
Nearest TSS
ENST00000437798/Upstream/89005; ENST00000495355/Downstream/9993;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/89008, chr2-CpG: 51/Downstream/23009
Upstream sequence
ttgtatttttagtagagatgagatttctctatgttggtcaggctggtctcgaactcccgacctcaggtgatctgcccgtctcagcttcccaaagtgctag
Downstream sequence
gattacaggcatgagccaccgcacctggccGCTCCTGGCTTTCAAACCTGTGTTGACTGATCAGAGAGGGAATGCACTCCTCTCAAAGACCCCAGAACCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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