Basic Information
VIS ID
TVIS44024844
Fusion event
HTLV-1-ATP6V1B1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
71163054/70935924 (Hg38)
End
71163054/70935924 (Hg38)
Orient
-
Location type
UTR5
Fragile sites / regions
FRA2S ; FRA2E
Target gene
ATP6V1B1
miRNAs that regulate target gene
hsa-mir-3175 ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-6827-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-4537 ; hsa-mir-1247-3p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-1321
Nearest miRNA
hsa-mir-1285-2/Upstream/682919; hsa-mir-10b/Downstream/4154888;
Nearest TSS
ENST00000437798/Upstream/3; ENST00000463380/Downstream/7450;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/28262, chr2-CpG: 43/Downstream/29040
Upstream sequence
gagggggagaggggaggggTGGCTGCAGGGGAAGGCTGAGCAGCTCTCTCCAGCTCCAGCTGGACCTGAAGTCTCAGAGCTGCCACCAGCAGCAGGCTCA
Downstream sequence
GACACTGGGCTCCCAGCTGGGGACTGCTCCATGGCCATGGAGATAGACAGCAGGCCTGGGGGGCTCCCCGGCAGTAGCTGCAACCTAGGTGCAGCCCGAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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