Basic Information
VIS ID
TVIS44024865
Fusion event
HTLV-1-CTNNA2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
GRCh37/hg19
Start
80351101/80123975 (Hg38)
End
80351101/80123975 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
CTNNA2
Nearest miRNA
hsa-mir-1285-2/Upstream/257392; hsa-mir-10b/Downstream/5659625;
Nearest TSS
ENST00000437798/Upstream/93424; ENST00000493024/Downstream/180299;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/610858, chr2-CpG: 101/Downstream/178577
Nearest cancer related gene
CTNNA2(TSG, No orient, 0)
Upstream sequence
GTAAAGAAATTGTCTGAGGGAAAACAGGGTACAGATTCTTAGGACTGGCCACATTCATTTGCATTTGGGCCCTGACCAAGCCCCCAGCACAGCCCAGCAG
Downstream sequence
GGGCTGTGATCCTCCTGTACACTGTGAGATAGATGCTTTTGAAATAGGCTAGAAAGGCAAGGAAGCAGGGTTGCTGCTGTTCACAAGCTCCCCTCTCTTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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