Basic Information
VIS ID
TVIS44024904
Fusion event
HTLV-1-REV1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
100035871/99419409 (Hg38)
End
100035871/99419409 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2A
Target gene
REV1
miRNAs that regulate target gene
hsa-mir-96-5p ; hsa-mir-21-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-155-5p
Nearest miRNA
hsa-mir-1285-2/Upstream/2621056; hsa-mir-10b/Downstream/1890041;
Nearest TSS
ENST00000437798/Upstream/6456; ENST00000434301/Downstream/5225;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/81472, chr2-CpG: 202/Downstream/69672
Upstream sequence
tccagccattctcctgcctcagcctcccgagtagctgggactacaggcgcccaccaccatgcccggctaatttttctgtatttttacagacggggtttca
Downstream sequence
ccatgttagccaggatggtctcgatctcctgacctcatgatccacccgcctcagcctcccaaagtgctgggactacaggaatgagccaccgtgcccAATC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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