Basic Information
VIS ID
TVIS44024915
Fusion event
HTLV-1-CBLB integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
105473363/105754519 (Hg38)
End
105473363/105754519 (Hg38)
Orient
+
Location type
Intronic
Target gene
CBLB
miRNAs that regulate target gene
hsa-mir-6885-3p ; hsa-mir-7162-5p ; hsa-mir-3977 ; hsa-mir-516b-3p ; hsa-mir-516a-3p ; hsa-mir-2115-5p ; hsa-mir-4762-5p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-765 ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-4635 ; hsa-mir-942-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-151b ; hsa-mir-151a-5p ; hsa-mir-891b
Nearest miRNA
hsa-let-7g/Upstream/2230403; hsa-mir-12124/Downstream/3848309;
Nearest TSS
ENST00000440867/Upstream/52343; ENST00000473550/Downstream/99127;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/385024, chr3-CpG: 84/Downstream/113916
Nearest cancer related gene
CBLB(OG, No orient, 0)
Upstream sequence
ATATCAATAGCAAATTGTTTTACAAATGTAGAAATTTCAGGGTGCTGGCAGAGACCTGGGAAGAAGAAAAGGGAagagagagagagagagagagagagag
Downstream sequence
agacagagagagagagagagagagagagagagagagagagaAAATAAAAAGGCCAACTAAACTCCAAGTTTTCACTAATCCAAAAATCTTTCAATATATT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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