Basic Information
VIS ID
TVIS44024923
Fusion event
HTLV-1-C3orf52 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
111812107/112093260 (Hg38)
End
111812107/112093260 (Hg38)
Orient
+
Location type
Intronic
Target gene
C3orf52
miRNAs that regulate target gene
hsa-mir-218-5p ; hsa-mir-4446-5p ; hsa-mir-629-3p ; hsa-mir-4279 ; hsa-mir-627-3p ; hsa-mir-4490 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-140-3p ; hsa-mir-188-3p ; hsa-mir-3674 ; hsa-mir-4433a-5p ; hsa-mir-4464 ; hsa-mir-4476 ; hsa-mir-4748 ; hsa-mir-5087 ; hsa-mir-5588-3p ; hsa-mir-6876-5p
Nearest miRNA
hsa-let-7g/Upstream/2490363; hsa-mir-12124/Downstream/19541;
Nearest TSS
ENST00000440867/Upstream/6822; ENST00000494096/Downstream/18192;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/6537, chr3-CpG: 40/Downstream/92275
Upstream sequence
CAGAGGATTTTCTTGCTAACTTCTTGATGAGGTTCTGTTCTGCCTCTGATCTCTCTTTTTGAAAACTTGATTCAGTAGAGTGTTGCCCTAAGGTCAGGGT
Downstream sequence
CTTGCTGCCTTCATTTCTGTGTCTCTGGCACATCCTAGGTATTCAGAACTGTCTGTTGCAACACAATGACTGCCTCACAATCTCCCTCTGCCTTTCTAGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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