Basic Information
VIS ID
TVIS44024940
Fusion event
HTLV-1-STXBP5L integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
120853507/121134660 (Hg38)
End
120853507/121134660 (Hg38)
Orient
-
Location type
Intronic
Target gene
STXBP5L
miRNAs that regulate target gene
hsa-mir-6083 ; hsa-mir-3692-3p ; hsa-mir-4436b-5p ; hsa-mir-6509-3p ; hsa-mir-5579-3p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-374c-3p ; hsa-mir-576-5p ; hsa-mir-4263 ; hsa-mir-1263 ; hsa-mir-150-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-660-3p ; hsa-mir-5193
Nearest miRNA
hsa-let-7g/Upstream/84945; hsa-mir-12124/Downstream/2027134;
Nearest TSS
ENST00000440867/Upstream/225089; ENST00000334384/Downstream/346936;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/225941, chr3-CpG: 41/Downstream/410962
Upstream sequence
ccaccccataacaggccctggtgtgtgatgttccccttcctgtgtccaagtgttctcattgttcaattcccgcctatgagtgagaacatgtggtgtttgg
Downstream sequence
ttttttgttcttgtgatagtttgctgagaatgatggtttccagcttcatccatgtccctgcaaaggacatgaactcatccttttttatgactgcatagta
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate