Basic Information
VIS ID
TVIS44024943
Fusion event
HTLV-1-SEC22A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
122945877/123227030 (Hg38)
End
122945877/123227030 (Hg38)
Orient
+
Location type
Intronic
Target gene
SEC22A
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-1976 ; hsa-mir-23a-5p ; hsa-mir-23b-5p ; hsa-mir-3653-5p ; hsa-mir-4279 ; hsa-mir-4722-3p ; hsa-mir-4740-3p ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6778-3p
Nearest miRNA
hsa-let-7g/Upstream/65151; hsa-mir-12124/Downstream/905899;
Nearest TSS
ENST00000440867/Upstream/18708; ENST00000609005/Downstream/50323;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/24763, chr3-CpG: 324/Downstream/220341
Upstream sequence
TCTAGAAATGAAAAATAGGTTCTTTGTACTGCATATTTATAGGCATGTAAAGTGCTTTGCATTTTGTTAAAATGGCTACATTCAAGGCCAGTGTTCTTGA
Downstream sequence
CTGTCACGGAAGGTGTAAATactttagtgatcgtctgctcaaacctcccatcccaaagaaggaatactatcgtcaacagttgtgaaatgatataaacttt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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