Basic Information
VIS ID
TVIS44024957
Fusion event
HTLV-1-KBTBD12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
127703271/127984428 (Hg38)
End
127703271/127984428 (Hg38)
Orient
-
Location type
UTR3
Target gene
KBTBD12
miRNAs that regulate target gene
hsa-mir-196b-3p ; hsa-mir-504-5p ; hsa-mir-4459 ; hsa-mir-6516-5p ; hsa-mir-3620-5p ; hsa-mir-1587 ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-455-3p ; hsa-mir-4417 ; hsa-mir-4741 ; hsa-mir-4675 ; hsa-mir-762 ; hsa-mir-5001-5p ; hsa-mir-4498 ; hsa-mir-6829-5p ; hsa-mir-4492 ; hsa-mir-4656 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-6087 ; hsa-mir-3192-5p ; hsa-mir-194-3p ; hsa-mir-7851-3p ; hsa-mir-490-3p ; hsa-mir-34b-3p ; hsa-mir-3614-5p ; hsa-mir-4722-5p ; hsa-mir-4768-3p ; hsa-mir-6500-3p
Nearest miRNA
hsa-let-7g/Upstream/397252; hsa-mir-12124/Downstream/862380;
Nearest TSS
ENST00000440867/Upstream/60347; ENST00000491668/Downstream/67213;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/68683, chr3-CpG: 82/Downstream/67470
Upstream sequence
ACGGAGAGGGCCCACAGCATCTCTGTCATGCCAGTCATGTGCACTGCATGCGTAGTGGCCTGTGTGTGAAGAAGCAGTGTGTGCTGGGCACTGGGTGGGG
Downstream sequence
AGCATGGGGAGTCTCCCTTCAGGGACTTCCCAGCCTGATAGGGTAAATAAGACACTACAAAGAAGAGGTGATGACGGCCACAGGAGGGGCACAGGGCCAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate