Basic Information
VIS ID
TVIS44024970
Fusion event
HTLV-1-WNT7A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
13904253/13862756 (Hg38)
End
13904253/13862756 (Hg38)
Orient
+
Location type
Intronic
Target gene
WNT7A
miRNAs that regulate target gene
hsa-mir-195-5p ; hsa-mir-497-5p ; hsa-mir-572 ; hsa-mir-664a-3p ; hsa-mir-5093 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-3941 ; hsa-mir-101-3p ; hsa-mir-603 ; hsa-mir-144-3p
Nearest miRNA
hsa-mir-12127/Upstream/3468194; hsa-let-7g/Downstream/1633483;
Nearest TSS
ENST00000440867/Upstream/212035; ENST00000432444/Downstream/12357;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/7948, chr3-CpG: 218/Downstream/15504
Nearest cancer related gene
WNT7A(TSG, No orient, 0)
Upstream sequence
GTGCAGGGAGCTGTGTCTGGGCGGAGCTTGGTAAGGTAACAGGCCCACAGCTCGGGAAACTGGGGAGGGGTGTGTGCAAGCCCCAGCCTCTGTCTTTCTC
Downstream sequence
CATCCAAGGGTCTCTCTTCCCACTGAGCAAGGCCAGAGCACACTGCTGACCACTTGCCAATGGTCAGCATCTACtccttcctggcttcacgcctttgcac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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