Basic Information
VIS ID
TVIS44024991
Fusion event
HTLV-1-MME integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q25.2
Reference genome
GRCh37/hg19
Start
154753573/155035784 (Hg38)
End
154753573/155035784 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA3D
Target gene
MME
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-26b-5p
Nearest miRNA
hsa-let-7g/Upstream/3469789; hsa-mir-1224/Downstream/4246862;
Nearest TSS
ENST00000440867/Upstream/11660; ENST00000497890/Downstream/43863;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/606608, chr3-CpG: 60/Downstream/43825
Nearby gene
MME(+43863) ;
Nearest cancer related gene
MME(TSG, No orient, 0)
Upstream sequence
gtttaagttcagcgtagctggcctgtagagaacattagggaaagtggaagagataaggtgagagaagtggaggggagaggctgcaccggggagcagatga
Downstream sequence
tgagggacctagcttcattggccattgtaagagaggtgtctcttattttgaaacagaaagttgccagtggagagttctgagcagagcaatgacatggata
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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