Basic Information
VIS ID
TVIS44024995
Fusion event
HTLV-1-PPM1L integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q25.33
Reference genome
End
160646143/160928355 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-21-5p ; hsa-mir-4728-5p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-3175 ; hsa-mir-8085 ; hsa-mir-6721-5p ; hsa-mir-6731-5p ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-4722-5p ; hsa-mir-3616-3p ; hsa-mir-6823-5p ; hsa-mir-4459 ; hsa-mir-3619-5p ; hsa-mir-761 ; hsa-mir-214-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-4779 ; hsa-mir-6165 ; hsa-mir-665 ; hsa-mir-3650 ; hsa-mir-7160-5p ; hsa-mir-3934-3p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-4790-3p ; hsa-mir-767-3p ; hsa-mir-4649-3p ; hsa-mir-3664-3p ; hsa-mir-4433a-3p ; hsa-mir-4768-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-6893-5p ; hsa-mir-940 ; hsa-mir-6808-5p ; hsa-mir-4695-5p ; hsa-mir-490-3p ; hsa-mir-6809-5p ; hsa-mir-31-5p ; hsa-mir-550b-3p ; hsa-mir-4501 ; hsa-mir-34c-3p ; hsa-mir-216a-5p ; hsa-mir-182-5p ; hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-138-2-3p ; hsa-mir-186-3p ; hsa-mir-103b ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-8056 ; hsa-mir-7977 ; hsa-mir-3165 ; hsa-mir-6880-5p ; hsa-mir-8071 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-138-5p ; hsa-mir-4456 ; hsa-mir-342-3p ; hsa-mir-383-3p ; hsa-mir-1228-3p
Nearest miRNA
hsa-let-7g/Upstream/523530; hsa-mir-1224/Downstream/3243116;
Nearest cancer related gene
PPM1L(TSG, No orient, 0)
Upstream sequence
TGGGGTTCAAGTATTTAATCTGCCTAGCACCCTTCTTCACTTCTAGCAACAGACTGCACACCCATCCTGACCACAGGGCATATGGCCTGGTACCTCACCT
Downstream sequence
CATctgaacacagtgattggctcaggaggtggtcacatgattgaaacagggccaactagagtcttcctgtgggatttttcaatgccatcctgacaggcgt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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