Basic Information
VIS ID
TVIS44025008
Fusion event
HTLV-1-SERPINI1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
167454908/167737120 (Hg38)
End
167454908/167737120 (Hg38)
Orient
-
Location type
Intronic
Target gene
SERPINI1
miRNAs that regulate target gene
hsa-mir-21-5p
Nearest miRNA
hsa-let-7g/Upstream/3565564; hsa-mir-1224/Downstream/814734;
Nearest TSS
ENST00000440867/Upstream/1395; ENST00000466865/Downstream/62926;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/2078, chr3-CpG: 123/Downstream/357921
Upstream sequence
TAACCAGGGTCAATAAAATGGAGTAATTGTCTTGTTTTCTCCTATTTCTATGCTTTCCTGAGTTCTCGGGATTTTAAATTTTATTTTTGTAATGCATCCC
Downstream sequence
AAATTTCTTTTTGAAAAGAAATGGCTCAAATGAATTCTCTTCCCAGATTAAAGTTCAGTCCTACTGAGTGCTACTACCGATAAGCCTAAGTGACTTTTCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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