Basic Information
VIS ID
TVIS44025027
Fusion event
HTLV-1-KLHL6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q27.1
Reference genome
GRCh37/hg19
Start
183254354/183536566 (Hg38)
End
183254354/183536566 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA3C
Target gene
KLHL6
miRNAs that regulate target gene
hsa-mir-10a-5p
Nearest miRNA
hsa-let-7g/Upstream/7021415; hsa-mir-1224/Downstream/350234;
Nearest TSS
ENST00000440867/Upstream/107788; ENST00000491676/Downstream/8219;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/44411, chr3-CpG: 154/Downstream/98880
Upstream sequence
aaagagcagccacctggctgttggcaggcagaggagggactggtgtctagtctgacctctgatgctcactcattgtgtgacttagtgcaagtgagtgaac
Downstream sequence
ctcagcttcctcatctgtaaaatggtataatagtccccacctcagtgagctgcacagaagaataagcaagatgaagtacaccaaggcgttagcacgatac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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