Basic Information
VIS ID
TVIS44025028
Fusion event
HTLV-1-YEATS2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q27.1
Reference genome
GRCh37/hg19
Start
183497590/183779802 (Hg38)
End
183497590/183779802 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA3C
Target gene
YEATS2
miRNAs that regulate target gene
hsa-mir-345-5p ; hsa-mir-378a-5p ; hsa-let-7b-5p ; hsa-mir-205-5p ; hsa-mir-155-5p
Nearest miRNA
hsa-let-7g/Upstream/7264651; hsa-mir-1224/Downstream/106998;
Nearest TSS
ENST00000440867/Upstream/3811; ENST00000497765/Downstream/18194;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/81521, chr3-CpG: 132/Downstream/44906
Upstream sequence
ttatatatttttttgagacacagccttgctctgtcgccaggctggagtgcagtggcacgatctcggctcactgcagcctccgcctcctgggttcaagcaa
Downstream sequence
ttctcctgcctcagcctcccgagtagctgggattacaggtgcccgccaccatgtccagctaatttttgtatttttactagagacggggtttcaccacgtt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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