Basic Information
VIS ID
TVIS44025035
Fusion event
HTLV-1-DGKG integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q27.2
Reference genome
GRCh37/hg19
Start
185956351/186238562 (Hg38)
End
185956351/186238562 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA3C
Target gene
DGKG
miRNAs that regulate target gene
hsa-mir-6083 ; hsa-mir-5011-5p ; hsa-mir-190a-3p ; hsa-mir-410-3p ; hsa-mir-1277-5p ; hsa-mir-1295b-3p ; hsa-mir-4789-5p ; hsa-mir-8485 ; hsa-mir-499a-5p ; hsa-mir-208b-3p ; hsa-mir-208a-3p
Nearest miRNA
hsa-let-7g/Upstream/470658; hsa-mir-1248/Downstream/548110;
Nearest TSS
ENST00000440867/Upstream/73595; ENST00000421006/Downstream/4075;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/44123, chr3-CpG: 94/Downstream/122359
Upstream sequence
TAAAGAATACTTGAGCACtatttttccttttcttttgctagacgacgatttccttgaaggcaggggccacatcttatgtgccctttattccAGATCACTT
Downstream sequence
TCAAACACTTTAGAATCTCAGTTGAATCAAATTTCTCTTTTGTTCTTTATGCCAACAGTGAGACGATAATCTCCCTAACATTCCTCAATTAGCAATTAAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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