Basic Information
VIS ID
TVIS44025041
Fusion event
HTLV-1-P3H2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q28
Reference genome
GRCh37/hg19
Start
189791514/190073725 (Hg38)
End
189791514/190073725 (Hg38)
Orient
-
Location type
Intronic
Target gene
P3H2
miRNAs that regulate target gene
hsa-mir-627-5p ; hsa-mir-3653-3p ; hsa-mir-570-3p ; hsa-mir-5197-3p ; hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-5572 ; hsa-mir-4260 ; hsa-mir-450a-2-3p ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-7109-5p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-6740-5p ; hsa-mir-6867-5p ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-891b ; hsa-mir-203b-3p ; hsa-mir-3689d ; hsa-mir-6825-5p ; hsa-mir-6851-5p ; hsa-mir-7106-5p ; hsa-mir-765 ; hsa-mir-7854-3p
Nearest miRNA
hsa-let-7g/Upstream/243716; hsa-mir-3137/Downstream/5060781;
Nearest TSS
ENST00000440867/Upstream/85960; ENST00000412203/Downstream/42923;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1125962, chr3-CpG: 99/Downstream/46566
Upstream sequence
GTGGTCAAGGATCATAGGCTGAGTGTAAATAGTAGGGCCAGAATTTCTAAGGCTCAGTTACGGCAAACTGAGTTTCATTTCAAAGCCAGTGGTATATATA
Downstream sequence
CATCCAATAAATGTATGCTTTTAAAAGAAGAGATGCTTGCAATAATGGAAATGATTCAACTGCAATCAAGGACTTTTGCTCTTTTTGTGCCAAGGCCATA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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