Basic Information
VIS ID
TVIS44025045
Fusion event
HTLV-1-ATP13A4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q29
Reference genome
GRCh37/hg19
Start
193309610/193591821 (Hg38)
End
193309610/193591821 (Hg38)
Orient
-
Location type
Intronic
Target gene
ATP13A4
miRNAs that regulate target gene
hsa-mir-9-3p ; hsa-mir-4480 ; hsa-mir-3659 ; hsa-mir-922 ; hsa-mir-759 ; hsa-mir-6513-3p ; hsa-mir-595 ; hsa-mir-4497 ; hsa-mir-1257 ; hsa-mir-3650 ; hsa-mir-4722-5p ; hsa-mir-1827 ; hsa-mir-4790-3p ; hsa-mir-4649-3p ; hsa-mir-4768-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-665 ; hsa-mir-7160-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-4478 ; hsa-mir-3929 ; hsa-mir-4419b ; hsa-mir-550b-2-5p ; hsa-mir-7703 ; hsa-mir-1287-3p ; hsa-mir-1227-3p ; hsa-mir-661 ; hsa-mir-4252 ; hsa-mir-5186 ; hsa-mir-4793-3p ; hsa-mir-1251-5p ; hsa-mir-1273g-3p ; hsa-mir-596 ; hsa-mir-4293 ; hsa-mir-5684 ; hsa-mir-5591-3p ; hsa-mir-4679 ; hsa-mir-4286 ; hsa-mir-6729-3p ; hsa-mir-660-5p ; hsa-mir-7843-3p ; hsa-mir-4786-3p
Nearest miRNA
hsa-let-7g/Upstream/3761812; hsa-mir-3137/Downstream/1542685;
Nearest TSS
ENST00000440867/Upstream/36699; ENST00000419435/Downstream/1290;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/350237, chr3-CpG: 39/Downstream/1214
Nearby gene
OPA1(+1323) ;
Upstream sequence
CCATATATAAATGGTGATGGTGGTTAGTTTCTCCTTTTTTTATGGTTAAAGTCTTTTATCCCTAATTTTTCTTTTTTGTTGTTGTTGTTAAAGTCTCTTG
Downstream sequence
GTTTCTCTTATTTTATTTTCTAAAATAACAAGGAAGTAACGATTACAAAGACACTTTTTGTACAACCCTACAATCCCAGGAAGATCTACAGTTTGCACAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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